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Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons
Botulinum neurotoxins (BoNTs) target presynaptic nerve terminals by recognizing specific neuronal surface receptors. Two homologous synaptic vesicle membrane proteins, synaptotagmins (Syts) I and II, bind toxins BoNT/B and G. However, a direct demonstration that Syts I/II mediate toxin binding and e...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2373501/ https://ncbi.nlm.nih.gov/pubmed/18158333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707184 |
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