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SV2 Mediates Entry of Tetanus Neurotoxin into Central Neurons

Tetanus neurotoxin causes the disease tetanus, which is characterized by rigid paralysis. The toxin acts by inhibiting the release of neurotransmitters from inhibitory neurons in the spinal cord that innervate motor neurons and is unique among the clostridial neurotoxins due to its ability to shuttl...

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Detalhes bibliográficos
Main Authors: Yeh, Felix L., Dong, Min, Yao, Jun, Tepp, William H., Lin, Guangyun, Johnson, Eric A., Chapman, Edwin R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991259/
https://ncbi.nlm.nih.gov/pubmed/21124874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001207
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