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SV2 Mediates Entry of Tetanus Neurotoxin into Central Neurons

Tetanus neurotoxin causes the disease tetanus, which is characterized by rigid paralysis. The toxin acts by inhibiting the release of neurotransmitters from inhibitory neurons in the spinal cord that innervate motor neurons and is unique among the clostridial neurotoxins due to its ability to shuttl...

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Bibliografske podrobnosti
Main Authors: Yeh, Felix L., Dong, Min, Yao, Jun, Tepp, William H., Lin, Guangyun, Johnson, Eric A., Chapman, Edwin R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991259/
https://ncbi.nlm.nih.gov/pubmed/21124874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001207
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