Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis

The E3 ubiquitin ligase synoviolin (SYVN1) functions as an anti-apoptotic factor that is responsible for the outgrowth of synovial cells during the development of rheumatoid arthritis. The molecular mechanisms underlying SYVN1 regulation of cell death are largely unknown. Here, we report that elevat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gao, Beixue, Lee, Sang-Myeong, Chen, An, Zhang, Jinping, Zhang, Donna D, Kannan, Krishnaswamy, Ortmann, Robert A, Fang, Deyu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373369/
https://ncbi.nlm.nih.gov/pubmed/18369366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.37
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados