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RANTES/CCL5 Induces Collagen Degradation by Activating MMP-1 and MMP-13 Expression in Human Rheumatoid Arthritis Synovial Fibroblasts

Regulated on activation, normal T expressed, and secreted (RANTES)/CC ligand 5 (CCL5) participates in rheumatoid arthritis (RA) pathogenesis by facilitating leukocyte infiltration, however, its other pathological functions are not fully defined in RA. In the present study, we evaluated the effect of...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Agere, Solomon A., Akhtar, Nahid, Watson, Jeffery M., Ahmed, Salahuddin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651228/
https://ncbi.nlm.nih.gov/pubmed/29093715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01341
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