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DNA substrate requirements for different activities of the human immunodeficiency virus type 1 integrase protein.

The integrase protein (IN) of human immunodeficiency virus type 1 removes two nucleotides from both 3' ends of the viral DNA (donor cleavage) and subsequently couples the newly generated 3' OH groups to phosphates in the target DNA (integration). The sequence requirements of IN for cleavag...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: van den Ent, F M, Vink, C, Plasterk, R H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC237244/
https://ncbi.nlm.nih.gov/pubmed/7966572
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