Effects of Mutations in Residues near the Active Site of Human Immunodeficiency Virus Type 1 Integrase on Specific Enzyme-Substrate Interactions

The phylogenetically conserved catalytic core domain of human immunodeficiency virus type 1 (HIV-1) integrase contains elements necessary for specific recognition of viral and target DNA features. In order to identify specific amino acids that determine substrate specificity, we mutagenized phylogen...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Gerton, Jennifer L., Ohgi, Sharron, Olsen, Mari, DeRisi, Joseph, Brown, Patrick O.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Animal Viruses
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110067/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573274/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.6.5046-5055.1998
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!