DNA substrate requirements for different activities of the human immunodeficiency virus type 1 integrase protein.

The integrase protein (IN) of human immunodeficiency virus type 1 removes two nucleotides from both 3' ends of the viral DNA (donor cleavage) and subsequently couples the newly generated 3' OH groups to phosphates in the target DNA (integration). The sequence requirements of IN for cleavage as well...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	van den Ent, F M, Vink, C, Plasterk, R H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966572/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.7825-7832.1994
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