Highly conservative reciprocal translocations formed by apparent joining of exchanged DNA double-strand break ends

Chromosomal translocations induced by ionizing radiation and radiomimetic drugs are thought to arise by incorrect joining of DNA double-strand breaks. To dissect such misrepair events at a molecular level, large-scale, bleomycin-induced rearrangements in the aprt gene of Chinese hamster ovary D422 c...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Peng, Zhou, Rui-Hua, Zou, Ying, Jackson-Cook, Colleen K., Povirk, Lawrence F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC23689/
https://ncbi.nlm.nih.gov/pubmed/9342355
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