Highly conservative reciprocal translocations formed by apparent joining of exchanged DNA double-strand break ends

Chromosomal translocations induced by ionizing radiation and radiomimetic drugs are thought to arise by incorrect joining of DNA double-strand breaks. To dissect such misrepair events at a molecular level, large-scale, bleomycin-induced rearrangements in the aprt gene of Chinese hamster ovary D422 c...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Wang, Peng, Zhou, Rui-Hua, Zou, Ying, Jackson-Cook, Colleen K., Povirk, Lawrence F.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23689/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9342355/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.22.12018
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