Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.

The replication competence of human immunodeficiency virus type 1 genomes containing mutations in the nef open reading frame was evaluated in continuous cell lines. Mutants that contained a deletion in the nef open reading frame, premature termination codons, or missense mutations in the N-terminal...

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Bibliografiske detaljer
Main Authors: Chowers, M Y, Spina, C A, Kwoh, T J, Fitch, N J, Richman, D D, Guatelli, J C
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC236779/
https://ncbi.nlm.nih.gov/pubmed/8151761
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