Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein.

Type 1 human immunodeficiency viruses encoding mutated nef reading frames are 10- to 30-fold less infectious than are isogenic viruses in which the nef gene is intact. This defect in infectivity causes nef-negative viruses to grow at an attenuated rate in vitro. To investigate the mechanism of Nef-m...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Pandori, M W, Fitch, N J, Craig, H M, Richman, D D, Spina, C A, Guatelli, J C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190360/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8676450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.7.4283-4290.1996
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