Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity.

The role of human immunodeficiency virus type 1 (HIV-1) accessory genes in pathogenesis has remained unclear because of the lack of a suitable in vivo model. The most controversial of these genes is nef. We investigated the requirement for Nef for in vivo replication and pathogenicity of two isolate...

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Main Authors: Jamieson, B D, Aldrovandi, G M, Planelles, V, Jowett, J B, Gao, L, Bloch, L M, Chen, I S, Zack, J A
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC236850/
https://ncbi.nlm.nih.gov/pubmed/8189487
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