Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity.

The role of human immunodeficiency virus type 1 (HIV-1) accessory genes in pathogenesis has remained unclear because of the lack of a suitable in vivo model. The most controversial of these genes is nef. We investigated the requirement for Nef for in vivo replication and pathogenicity of two isolate...

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Pubblicato in:	J Virol
Autori principali:	Jamieson, B D, Aldrovandi, G M, Planelles, V, Jowett, J B, Gao, L, Bloch, L M, Chen, I S, Zack, J A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236850/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8189487/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.6.3478-3485.1994
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