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A new score statistic to test for association given linkage in affected sibling pair-control designs

To detect association of the DR1 allele with rheumatoid arthritis (RA) given linkage in the affected sibling pairs of the replicates of Problem 3 of Genetic Analysis Workshop 15 (GAW15), we propose a new score statistic that takes into account the linkage information. We knew the answers. Linkage st...

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Main Authors: Houwing-Duistermaat, Jeanine J, Uh, Hae Won, van Houwelingen, Hans C
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367608/
https://ncbi.nlm.nih.gov/pubmed/18466537
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