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How to quantify information loss due to phase ambiguity in haplotype case-control studies

Assigning haplotypes in a case-control study is a challenging problem. We proposed a method to quantify the information loss due to missing phase information. We determined which individuals were responsible for the information loss, and calculated how much information could be gained when the ambig...

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Библиографические подробности
Главные авторы: Uh, Hae-Won, Houwing-Duistermaat, Jeanine J, Putter, Hein, van Houwelingen, Hans C
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2005
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866831/
https://ncbi.nlm.nih.gov/pubmed/16451564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S108
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