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Assessment of global phase uncertainty in case-control studies

BACKGROUND: In haplotype-based candidate gene studies a problem is that the genotype data are unphased, which results in haplotype ambiguity. The [Image: see text] measure [1] quantifies haplotype predictability from genotype data. It is computed for each individual haplotype, and for a measure of g...

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Detalhes bibliográficos
Main Authors: Uh, Hae-Won, Houwing-Duistermaat, Jeanine J, Putter, Hein, van Houwelingen, Hans C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760579/
https://ncbi.nlm.nih.gov/pubmed/19751505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-10-54
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