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Thermodynamic and Kinetic Properties of Amino-Terminal and S4-S5 Loop HERG Channel Mutants under Steady-State Conditions

Gating kinetics and underlying thermodynamic properties of human ether-a-go-go-related gene (HERG) K(+) channels expressed in Xenopus oocytes were studied using protocols able to yield true steady-state kinetic parameters. Channel mutants lacking the initial 16 residues of the amino terminus before...

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Bibliografski detalji
Glavni autori: Alonso-Ron, Carlos, de la Peña, Pilar, Miranda, Pablo, Domínguez, Pedro, Barros, Francisco
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367168/
https://ncbi.nlm.nih.gov/pubmed/18222997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.116731
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