TGFβ/Activin/Nodal Pathway in Inhibition of Human Embryonic Stem Cell Differentiation by Mechanical Strain

Cyclic biaxial mechanical strain has been reported to inhibit human embryonic stem cell differentiation without selecting against survival of differentiated or undifferentiated cells. We show that TGFβ/Activin/Nodal signaling plays a crucial role in repression of human embryonic stem cell (hESC) dif...

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Main Authors: Saha, Somen, Ji, Lin, de Pablo, Juan J., Palecek, Sean P.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2008
Teme:
Cell Biophysics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367167/
https://ncbi.nlm.nih.gov/pubmed/18234825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.119891
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