TGFβ/Activin/Nodal Pathway in Inhibition of Human Embryonic Stem Cell Differentiation by Mechanical Strain

Cyclic biaxial mechanical strain has been reported to inhibit human embryonic stem cell differentiation without selecting against survival of differentiated or undifferentiated cells. We show that TGFβ/Activin/Nodal signaling plays a crucial role in repression of human embryonic stem cell (hESC) dif...

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Autori principali: Saha, Somen, Ji, Lin, de Pablo, Juan J., Palecek, Sean P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2008
Soggetti:
Cell Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367167/
https://ncbi.nlm.nih.gov/pubmed/18234825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.119891
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