Design, Synthesis, and Characterization of a Dual Modality Positron Emission Tomography Fluorescence Imaging Agent for Monoclonal Antibody Tumor-Targeted Imaging

A novel lysine-based trifunctional chelate 3 was designed, synthesized, and characterized, which bears both a chelating moiety (CHX-A”) for sequestering radiometals ((86)Y or (111)In) and the near infrared dye Cy5.5 for dual modality PET (or SPECT) and fluorescence imaging, respectively. Successful...

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Detaylı Bibliyografya
Asıl Yazarlar: Xu, Heng, Baidoo, Kwamena, Gunn, Andrew J., Boswell, C. Andrew, Milenic, Diane E., Choyke, Peter L., Brechbiel, Martin W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366096/
https://ncbi.nlm.nih.gov/pubmed/17725340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm070657w
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