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Towards Preparation of Antibody-based Imaging Probe Libraries for Dual-modality Positron Emission Tomography and Fluorescence Imaging
Two novel imaging agents trastuzumab-Cy5.5-CHX-A″ 1 and cetuximab-Cy7-CHX-A″ 2, bearing both a chelating moiety (CHX-A″) for sequestering metallic radionuclides ((86)Y or (111)In) and the near infrared dye Cy5.5/Cy7, were prepared by a novel modular synthetic strategy as examples of dual-labeled, an...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759299/ https://ncbi.nlm.nih.gov/pubmed/19505829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.05.048 |
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