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Design, Synthesis, and Characterization of a Dual Modality Positron Emission Tomography Fluorescence Imaging Agent for Monoclonal Antibody Tumor-Targeted Imaging
A novel lysine-based trifunctional chelate 3 was designed, synthesized, and characterized, which bears both a chelating moiety (CHX-A”) for sequestering radiometals ((86)Y or (111)In) and the near infrared dye Cy5.5 for dual modality PET (or SPECT) and fluorescence imaging, respectively. Successful...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366096/ https://ncbi.nlm.nih.gov/pubmed/17725340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm070657w |
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