Binding of MutS protein to oligonucleotides containing a methylated or an ethylated guanine residue, and correlation with mutation frequency

The MutS-based mismatch repair (MMR) system has been conserved from prokaryotes to humans, and plays important roles in maintaining the high fidelity of genomic DNA. MutS protein recognizes several different types of modified base pairs, including methylated guanine-containing base pairs. Here, we l...

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Autors principals: Taira, Kentaro, Nakamura, Shintaro, Nakano, Khota, Maehara, Daisuke, Okamoto, Keinosuke, Arimoto, Sakae, Loakes, David, Worth, Leroy, Schaaper, Roel M., Seio, Kohji, Sekine, Mitsuo, Negishi, Kazuo, Negishi, Tomoe
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365708/
https://ncbi.nlm.nih.gov/pubmed/18243250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2007.12.009
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