Saturation of DNA mismatch repair and error catastrophe by a base analogue in Escherichia coli.

Deoxyribosyl-dihydropyrimido[4,5-c][1,2]oxazin-7-one (dP) is a potent mutagenic deoxycytidine-derived base analogue capable of pairing with both A and G, thereby causing G. C --> A. T and A. T --> G. C transition mutations. We have found that the Escherichia coli DNA mismatch-repair system can...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Negishi, Kazuo, Loakes, David, Schaaper, Roel M
Format: Artigo
Jezik:Inglês
Izdano: 2002
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462219/
https://ncbi.nlm.nih.gov/pubmed/12196386
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki