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Chromosomal directionality of DNA mismatch repair in Escherichia coli
Defects in DNA mismatch repair (MMR) result in elevated mutagenesis and in cancer predisposition. This disease burden arises because MMR is required to correct errors made in the copying of DNA. MMR is bidirectional at the level of DNA strand polarity as it operates equally well in the 5′ to 3′ and...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4522816/ https://ncbi.nlm.nih.gov/pubmed/26170312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505370112 |
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