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Mismatch repair at stop codons is directed independent of GATC methylation on the Escherichia coli chromosome

The mismatch repair system (MMR) corrects replication errors that escape proofreading. Previous studies on extrachromosomal DNA in Escherichia coli suggested that MMR uses hemimethylated GATC sites to identify the newly synthesized strand. In this work we asked how the distance of GATC sites and the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sneppen, Kim, Semsey, Szabolcs
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376664/
https://ncbi.nlm.nih.gov/pubmed/25475788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07346
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