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Mismatch repair at stop codons is directed independent of GATC methylation on the Escherichia coli chromosome

The mismatch repair system (MMR) corrects replication errors that escape proofreading. Previous studies on extrachromosomal DNA in Escherichia coli suggested that MMR uses hemimethylated GATC sites to identify the newly synthesized strand. In this work we asked how the distance of GATC sites and the...

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Publicado en:Sci Rep
Main Authors: Sneppen, Kim, Semsey, Szabolcs
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376664/
https://ncbi.nlm.nih.gov/pubmed/25475788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07346
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