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Preferential exclusion of sucrose from recombinant interleukin-1 receptor antagonist: Role in restricted conformational mobility and compaction of native state

Understanding the mechanism for sucrose-induced protein stabilization is important in many diverse fields, ranging from biochemistry and environmental physiology to pharmaceutical science. Timasheff and Lee [Lee, J. C. & Timasheff, S. N. (1981) J. Biol. Chem. 256, 7193–7201] have established tha...

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Detalhes bibliográficos
Main Authors: Kendrick, Brent S., Chang, Byeong S., Arakawa, Tsutomu, Peterson, Brian, Randolph, Theodore W., Manning, Mark C., Carpenter, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23655/
https://ncbi.nlm.nih.gov/pubmed/9342337
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