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Effects of sucrose on conformational equilibria and fluctuations within the native-state ensemble of proteins

Osmolytes increase the thermodynamic conformational stability of proteins, shifting the equilibrium between native and denatured states to favor the native state. However, their effects on conformational equilibria within native-state ensembles of proteins remain controversial. We investigated the e...

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Main Authors: Kim, Yong-Sung, Jones, Latoya S., Dong, Aichun, Kendrick, Brent S., Chang, Byeong S., Manning, Mark C., Randolph, Theodore W., Carpenter, John F.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323899/
https://ncbi.nlm.nih.gov/pubmed/12761396
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