Antitumor Trans Platinum Adducts of GMP and AMP

Recently it has been shown that several analogues of the clinically ineffective trans-DDP exhibit antitumor activity comparable to that of cis-DDP. The present paper describes the binding of antitumor trans-[PtCl(2)(E-iminoether)(2)] (trans-EE) to guanosinemonophosphate (GMP) and adenosinemonophosph...

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Autors principals: Liu, Yangzhong, Sivo, Maria F., Natile, Giovanni, Sletten, Einar
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2000
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365223/
https://ncbi.nlm.nih.gov/pubmed/18475942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.2000.169
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