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Towards Antitumor Active trans-Platinum Compounds
Substitution of NH(3) by a range of amines in trans-[PtCl(2)(NH(3))(2)] produces compounds with cytotoxicity significantly improved over the parent transplatin and in many cases equivalent to that of cisplatin. This microreview summarizes the chemistry and biology of trans-platinum compounds contain...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2821104/ https://ncbi.nlm.nih.gov/pubmed/20161688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejic.200801118 |
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