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Inhibition of transcription by platinum antitumor compounds
Cisplatin, carboplatin, and oxaliplatin are three FDA-approved members of the platinum anticancer drug family. These compounds induce apoptosis in tumor cells by binding to nuclear DNA, forming a variety of structural adducts and triggering cellular responses, one of which is the inhibition of trans...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752884/ https://ncbi.nlm.nih.gov/pubmed/20046924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b907567d |
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