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Transcription Inhibition by Platinum DNA Cross-links in Live Mammalian Cells

We have investigated the processing of site-specific Pt-DNA cross-links in live mammalian cells to enhance our understanding of the mechanism of action of platinum-based anticancer drugs. The activity of platinum drugs against cancer is mediated by a combination of processes including cell entry, dr...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ang, Wee Han, Myint, MyatNoeZin, Lippard, Stephen J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877768/
https://ncbi.nlm.nih.gov/pubmed/20443565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja101495v
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