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Preparation of Mammalian Expression Vectors Incorporating Site-Specifically Platinated-DNA Lesions
FDA-approved platinum-based anticancer drugs, cisplatin, carboplatin and oxaliplatin, are some of the most effective chemotherapies in clinical use. The cytotoxic action of these compounds against cancer requires a combination of processes including cell entry, drug activation, DNA binding and trans...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765503/ https://ncbi.nlm.nih.gov/pubmed/19351185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900031a |
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