DNA adducts of antitumor trans-[PtCl2 (E-imino ether)2].

It has been shown recently that some analogues of clinically ineffective trans-diamminedichloroplatinum (II) (transplatin) exhibit antitumor activity. This finding has inverted the empirical structure-antitumor activity relationships delineated for platinum(II) complexes, according to which only the...

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Hauptverfasser: Brabec, V, Vrána, O, Nováková, O, Kleinwächter, V, Intini, F P, Coluccia, M, Natile, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC145631/
https://ncbi.nlm.nih.gov/pubmed/8628659
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