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FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
Autophagy is a membrane-mediated intracellular degradation system. The serine/threonine kinase Atg1 plays an essential role in autophagosome formation. However, the role of the mammalian Atg1 homologues UNC-51–like kinase (ULK) 1 and 2 are not yet well understood. We found that murine ULK1 and 2 loc...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2364687/ https://ncbi.nlm.nih.gov/pubmed/18443221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200712064 |
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