Laminin γ1 chain peptide, C-16 (KAFDITYVRLKF), promotes migration, MMP-9 secretion, and pulmonary metastasis of B16–F10 mouse melanoma cells

Laminin-1, a heterotrimer of α1, β1, and γ1 chains specific to basement membrane, promotes cell adhesion and migration, proteinase secretion and metastases of tumour cells. Several active sites on the α1 chain have been found to promote B16–F10 melanoma lung colonisation and here we have determined...

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Main Authors: Kuratomi, Y, Nomizu, M, Tanaka, K, Ponce, M L, Komiyama, S, Kleinman, H K, Yamada, Y
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2002
主題:
Experimental Therapeutics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364181/
https://ncbi.nlm.nih.gov/pubmed/11953867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600187
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