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Differentiation-dependent photodynamic therapy regulated by porphobilinogen deaminase in B16 melanoma
Protoporphyrin IX (PpIX) synthesis by malignant cells is clinically exploited for photodiagnosis and photodynamic therapy following administration of 5-aminolevulinic acid (ALA). The expression and activity of the housekeeping porphobilinogen deaminase (PBGD) was correlated to PpIX synthesis in diff...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409749/ https://ncbi.nlm.nih.gov/pubmed/15150593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601760 |
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