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Differentiation-dependent photodynamic therapy regulated by porphobilinogen deaminase in B16 melanoma

Protoporphyrin IX (PpIX) synthesis by malignant cells is clinically exploited for photodiagnosis and photodynamic therapy following administration of 5-aminolevulinic acid (ALA). The expression and activity of the housekeeping porphobilinogen deaminase (PBGD) was correlated to PpIX synthesis in diff...

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Main Authors: Ickowicz Schwartz, D, Gozlan, Y, Greenbaum, L, Babushkina, T, Katcoff, D J, Malik, Z
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409749/
https://ncbi.nlm.nih.gov/pubmed/15150593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601760
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