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Laminin γ1 chain peptide, C-16 (KAFDITYVRLKF), promotes migration, MMP-9 secretion, and pulmonary metastasis of B16–F10 mouse melanoma cells

Laminin-1, a heterotrimer of α1, β1, and γ1 chains specific to basement membrane, promotes cell adhesion and migration, proteinase secretion and metastases of tumour cells. Several active sites on the α1 chain have been found to promote B16–F10 melanoma lung colonisation and here we have determined...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kuratomi, Y, Nomizu, M, Tanaka, K, Ponce, M L, Komiyama, S, Kleinman, H K, Yamada, Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364181/
https://ncbi.nlm.nih.gov/pubmed/11953867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600187
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