CAG and GGC repeat polymorphisms in the androgen receptor gene and breast cancer susceptibility in BRCA1/2 carriers and non-carriers

Variation in the penetrance estimates for BRCA1 and BRCA2 mutations carriers suggests that other genetic polymorphisms may modify the cancer risk in carriers. A previous study has suggested that BRCA1 carriers with longer lengths of the CAG repeat in the androgen receptor (AR) gene are at increased...

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Bibliographic Details
Main Authors: Kadouri, L, Easton, D F, Edwards, S, Hubert, A, Kote-Jarai, Z, Glaser, B, Durocher, F, Abeliovich, D, Peretz, T, Eeles, R A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2001
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363908/
https://ncbi.nlm.nih.gov/pubmed/11437399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1777
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