CDX2 mutations do not account for juvenile polyposis or Peutz–Jeghers syndrome and occur infrequently in sporadic colorectal cancers

Peutz–Jeghers syndrome (PJS) and juvenile polyposis (JPS) are both characterized by the presence of hamartomatous polyps and increased risk of malignancy in the gastrointestinal tract. Mutations of the LKB1 and SMAD4 genes have been shown recently to cause a number of PJS and JPS cases respectively,...

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Detalhes bibliográficos
Main Authors: Woodford-Richens, K L, Halford, S, Rowan, A, Bevan, S, Aaltonen, L A, Wasan, H, Bicknell, D, Bodmer, W F, Houlston, R S, Tomlinson, I P M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363639/
https://ncbi.nlm.nih.gov/pubmed/11355940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1800
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