Mucosal prolapse in the pathogenesis of Peutz‐Jeghers polyposis

Germline mutations in LKB1 cause the rare cancer prone disorder Peutz‐Jeghers syndrome (PJS). Gastrointestinal hamartomatous polyps constitute the major phenotypic trait in PJS. Hamartomatous polyps arising in PJS patients are generally considered to lack premalignant potential although rare neoplas...

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Autori principali: Jansen, M, de Leng, W W J, Baas, A F, Myoshi, H, Mathus‐Vliegen, L, Taketo, M M, Clevers, H, Giardiello, F M, Offerhaus, G J A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2006
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Leading Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856361/
https://ncbi.nlm.nih.gov/pubmed/16344569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.069062
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