Mucosal prolapse in the pathogenesis of Peutz‐Jeghers polyposis

Germline mutations in LKB1 cause the rare cancer prone disorder Peutz‐Jeghers syndrome (PJS). Gastrointestinal hamartomatous polyps constitute the major phenotypic trait in PJS. Hamartomatous polyps arising in PJS patients are generally considered to lack premalignant potential although rare neoplas...

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Detalhes bibliográficos
Main Authors: Jansen, M, de Leng, W W J, Baas, A F, Myoshi, H, Mathus‐Vliegen, L, Taketo, M M, Clevers, H, Giardiello, F M, Offerhaus, G J A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Leading Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856361/
https://ncbi.nlm.nih.gov/pubmed/16344569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.069062
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