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Mucosal prolapse in the pathogenesis of Peutz‐Jeghers polyposis

Germline mutations in LKB1 cause the rare cancer prone disorder Peutz‐Jeghers syndrome (PJS). Gastrointestinal hamartomatous polyps constitute the major phenotypic trait in PJS. Hamartomatous polyps arising in PJS patients are generally considered to lack premalignant potential although rare neoplas...

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Bibliographic Details
Main Authors: Jansen, M, de Leng, W W J, Baas, A F, Myoshi, H, Mathus‐Vliegen, L, Taketo, M M, Clevers, H, Giardiello, F M, Offerhaus, G J A
Format: Artigo
Language:Inglês
Published: BMJ Group 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856361/
https://ncbi.nlm.nih.gov/pubmed/16344569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.069062
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