STRAD in Peutz-Jeghers syndrome and sporadic cancers

Background/Aims: LKB1 is a tumour suppressor gene that is associated with Peutz-Jeghers syndrome (PJS), a rare autosomal dominant cancer predisposition syndrome. However, germline mutations in the LKB1 gene are found in only about 60% of patients with PJS, suggesting the existence of a second PJS ge...

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Detalhes bibliográficos
Main Authors: de Leng, W W J, Keller, J J, Luiten, S, Musler, A R, Jansen, M, Baas, A F, de Rooij, F W M, Gille, J J P, Menko, F H, Offerhaus, G J A, Weterman, M A J
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 Journal of Clinical Pathology 2005
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770744/
https://ncbi.nlm.nih.gov/pubmed/16189157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2005.026013
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