The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression

Genes of the polycomb group function by silencing homeotic selector genes that regulate embryogenesis. In mice, downregulation of one of the polycomb genes, bmi-1, leads to neurological alterations and severe proliferative defects in lymphoid cells, whilst bmi-1 overexpression, together with upregul...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Vonlanthen, S, Heighway, J, Altermatt, H J, Gugger, M, Kappeler, A, Borner, M M, Lohuizen, M van, Betticher, D C
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2001
Sujets:
Regular Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363629/
https://ncbi.nlm.nih.gov/pubmed/11355949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1791
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