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Chromosome instability in fibroblasts derived from Li–Fraumeni syndrome families without TP53 mutations

The mean in vitro lifespan of dermal fibroblast strains derived from cancer-affected individuals belonging to families conforming to the classical Li-Fraumeni-syndrome or the Li-Fraumeni-like syndrome (LF strains), but in whom no TP53 mutation has been found, was not significantly different to that...

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Detalhes bibliográficos
Main Authors: Boyle, J M, Spreadborough, A, Greaves, M J, Birch, J M, Scott, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363597/
https://ncbi.nlm.nih.gov/pubmed/11027425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1444
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