Loading...

Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families.

Previous work has indicated a role for p53 in cell cycle control, genomic stability and cellular responses to DNA-damaging agents. However, few data are available for human fibroblasts heterozygous for defined germline mutations in TP53. We report studies on 25 strains derived from 12 families with...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Boyle, J. M., Mitchell, E. L., Greaves, M. J., Roberts, S. A., Tricker, K., Burt, E., Varley, J. M., Birch, J. M., Scott, D.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150396/
https://ncbi.nlm.nih.gov/pubmed/9649131
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!