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Radiation-induced G(1) arrest is not defective in fibroblasts from Li-Fraumeni families without TP53 mutations

Radiation-induced G(1) arrest was studied in four classes of early passage skin fibroblasts comprising 12 normals, 12 heterozygous (mut/wt) TP53 mutation-carriers, two homozygous (mut/–) TP53 mutation-carriers and 16 strains from nine Li-Fraumeni syndrome or Li-Fraumeni-like families in which no TP5...

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Bibliografische gegevens
Hoofdauteurs: Boyle, J M, Greaves, M J, Camplejohn, R S, Birch, J M, Roberts, S A, Varley, J M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1999
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362814/
https://ncbi.nlm.nih.gov/pubmed/10206274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690265
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