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High rates of frameshift mutations within homo-oligomeric runs during a single cycle of retroviral replication.

Homo-oligomeric runs were inserted into a spleen necrosis virus-based retrovirus vector to determine the nature and rate of mutations within runs of 10 to 12 identical nucleotides during a single replication cycle. Clones of helper cells containing integrated copies of retroviral vectors were used t...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Burns, D P, Temin, H M
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1994
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236342/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7515970/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.7.4196-4203.1994
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